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PharmaSUG proceedings: Statistics and Pharmacokinetics, 187 papers

Pharmaceutical SAS Users Group 2017   May 14-17, 2017 - Baltimore, Maryland

Statistics and Pharmacokinetics
Best Paper
tweet!  Multiple Imputation: A Statistical Programming Story
  Chris Smith, Cytel Inc.; Scott Kosten, DataCeutics Inc.
Keywords: Multiple Imputation PROC MI PROC MIANALYZE FCS MCMC MONOTONE sensitivity analysis missing data
Pages: 16 Size: 527 Kb 
tweet!  Multiplicity Controlled Analyses Using SAS/IML
  Xingxing Wu, Eli Lilly and Company; Hangtao Xu, Eli Lilly and Company
Keywords: Multiplicity Controlled Analyses Graphical Approach SAS/IML
Pages: 8 Size: 339 Kb 
tweet!  Population PK/PD Analysis - SAS® with R and NONMEM® Make Customization Easy
  Sharmeen Reza, Cytel Inc.
Keywords: PK/PD Population PK/PD NONMEM PK Customization PD Customization Population PK/PD Customization
Pages: 11 Size: 638 Kb 
tweet!  Combining Survival Analysis Results after Multiple Imputation of Censored Event Times
  Jonathan L Moscovici, QuintilesIMS; Bohdana Ratitch, QuintilesIMS
Pages: 11 Size: 758 Kb 
tweet!  Adverse Event Data over Time
  Kriss Harris, SAS Specialists Ltd
Keywords: Temkin Graph Template Language Probability of Being in Best Response Function PBRF Adverse Events TEAE AE Treatment Emergent Adverse Events
Pages: 11 Size: 733 Kb 

Pharmaceutical SAS Users Group 2016   May 8-11, 2016 - Denver, Colorado

Statistics and Pharmacokinetics
tweet!  Cox proportional hazards regression to model the risk of outcomes per double increase in a continuous explanatory variable
  Seungyoung Hwang, Johns Hopkins University, Baltimore, MD
Keywords: SAS doubling Cox proportional hazards model
Pages: 4 Size: 114 Kb 
tweet!  Programming Support for Exposure-Response Analysis in Oncology Drug Development
  Peter Lu, Novartis Pharmaceuticals Corporation, East Hanover, NJ; Hong Yan, Novartis Pharmaceuticals Corporation, East Hanover, NJ
Keywords: Programming Exposure Response Oncology
Pages: 8 Size: 386 Kb 
tweet!  Scrambled Data – A Population PK/PD Programming Solution
  Sharmeen Reza, Cytel Inc., Cambridge, MA
Keywords: NONMEM Pop-PK/PD Scramble Scrambling Population PK/PD Programming Data Transfer PK Analysis
Pages: 8 Size: 363 Kb 
tweet!  Unequalslopes: Making life easier when the proportional odds assumption fails
  Matthew Wiedel, inVentiv Health, Lincoln, NE
Keywords: logistic unequalslopes logit
Pages: 11 Size: 621 Kb 
tweet!  A Dose Escalation Method for Dual-Agent in Phase 1 Cancer Clinical Trial using the SAS MCMC Procedure
  Gwénaël Le Teuff, Gustave Roussy, Paris, France; Mohamed Amine Bayar, Gustave Roussy, Paris, France
Keywords: Dose finding Phase I trial Bayesian design MCMC procedure
Pages: 14 Size: 120 Kb 
Best Paper
tweet!  Latent Structure Analysis Procedures in SAS®
  Deanna Schreiber-Gregory, National University, Moorhead, MN
Keywords: latent analysis structural equation modeling LTA LCA TRAJ CALIS
Pages: 8 Size: 527 Kb 
tweet!  Everything or Nothing - A Better Confidence Intervals for Binomial Proportion in Clinical Trial Data Analysis
  Sakthivel Sivam, Quartesian LLC, Princeton, NJ; Subbiah Meenakshisundaram, L.N Government College, Ponneri, India
Keywords: Binomial proportion Confidence interval Score Interval Approach Boundary
Pages: 8 Size: 371 Kb 
tweet!  Simulation of Data using the SAS System, Tools for Learning and Experimentation
  Kevin R. Viel, Ph.D., inVentiv Health Clinical, Atlanta, GA
Keywords: Survival analysis time-to-event simulation random number generator seed RANNOR RANBIN RANUNI logistic regression Weibull distribution zero-inflated Poisson ZIP NLMIXED
Pages: 11 Size: 159 Kb 
tweet!  “I Want the Mean, But not That One!”
  David Franklin, Quintiles Real Late Phase Research, Cambridge, MA
Keywords: Statistic Mean
Pages: 5 Size: 207 Kb 
tweet!  ROC Curve: Making way for correct diagnosis
  Manoj Pandey, Ephicacy Lifescience Analytics Pvt. Ltd., Bangalore, India; Abhinav Jain, Ephicacy Consulting Group Inc., Iselin, NJ
Keywords: Sensitivity Specificity Receiver Operating Characteristics Area under Curve Optimal Cut-off Point Youden Index
Pages: 12 Size: 1040 Kb 

Pharmaceutical SAS Users Group 2015   May 17-20, 2015 - Orlando, Florida

Statistics and Pharmacokinetics
tweet!  Multilevel Randomization
  Marina Komaroff, Noven Pharmaceuticals, New York, NY; Lois Lynn, Noven Pharmaceuticals, New York, NY
Pages: 10 Size: 578 Kb 
tweet!  MMRM: Macro for Selecting Best Covariance Structure with the Method of Interest
  Linga Reddy Baddam, inVentiv Health Clinical, Hyderabad, India; Sudarshan Reddy Shabadu, inVentiv Health Clinical, Hyderabad, India; Chunxue Shi, inVentiv Health Clinical, Maryland, USA
Keywords: MMRM Mixed Model Repeated Measures Missing at Random pattern (MAR) macro
Pages: 7 Size: 84 Kb 
tweet!  Missing Data For Repeated Measures: Single Imputation VS Multiple Imputation
  Giulia Tonini, PhD Menarini Ricerche, Florence, Italy; Simona Scartoni, Menarini Ricerche, Florence, Italy; Camilla Paoli, Menarini Ricerche, Florence, Italy; Andrea Nizzardo, Menarini Ricerche, Florence, Italy; Angela Capriati, MD, PhD, Menarini Ricerche, Florence, Italy
Pages: 10 Size: 338 Kb 
tweet!  Means Comparisons and No Hard Coding of Your Coefficient Vector – It Really Is Possible!
  Frank Tedesco, United Biosource Corporation, Blue Bell, PA
Pages: 8 Size: 57 Kb 
Best Paper
tweet!  Using ANCOVA to Assess Regression to the Mean
  Kathryn Schurr, M.S., Spectrum Health – Healthier Communities, Grand Rapids, MI
Pages: 9 Size: 431 Kb 
tweet!  Confidence Intervals Are a Programmer’s Friend
  Xinxin Guo, Quintiles, Cambridge, MA; Zhaohui Su, Quintiles, Cambridge, MA
Pages: 8 Size: 313 Kb 
tweet!  Growing Needs in Drug Industry for NONMEM Programmers Using SAS®
  Sharmeen Reza, Cytel Inc., Cambridge, MA
Keywords: NONMEM Programmers Drug Industry SAS Grow
Pages: 11 Size: 394 Kb 
tweet!  How To Use Latent Analyses Within Survey Data Can Be Valuable Additions to Any Regression Model
  Deanna Schreiber-Gregory, National University, La Jolla, CA
Pages: 9 Size: 73 Kb 
Current Methods in Survival Analysis Using SAS/STAT® Software
  Changbin Guo, SAS
tweet!  %PIC_NPMLE: A SAS Macro For Nonparametric Estimation In Partly Interval-Censored Survival Data
  Liang Zhu, St. Jude Children’s Research Hospital, Memphis, TN; Yimei Li, St. Jude Children’s Research Hospital, Memphis, TN; Qinlei Huang, St. Jude Children’s Research Hospital, Memphis, TN
Keywords: macro
Pages: 12 Size: 556 Kb 

Pharmaceutical SAS Users Group 2014   June 1-4, 2014 - San Diego, California

Statistics & Pharmacokinetics
tweet!  Factor Analysis of Scale for Assessment of Negative Symptoms using SAS Software
  Ben Adeyi, Shire Pharmaceuticals, Chesterbrook, PA; David Shen, Independent Consultant, Chesterbrook, PA
Pages: 8 Size: 97 Kb 
tweet!  Handling with missing data in clinical trials for time-to-event variables
  Giulia Tonini,PhD Menarini Ricerche, Florence, Italy; Simona Scartoni, Menarini Ricerche, Florence, Italy; Angela Capriati, MD, PhD, Menarini Ricerche, Florence, Italy
Pages: 9 Size: 387 Kb 
tweet!  Defining Non-Inferiority Margins for Skin Adhesion Studies
  Marina Komaroff, Noven Pharmaceuticals, New York, NY; Sailaja Bhaskar, Noven Pharmaceuticals, New York, NY
Pages: 12 Size: 575 Kb 
Best Paper
tweet!  %IC_LOGISTIC: A SAS® Macro to Produce Sorted Information Criteria (AIC/BIC) List for PROC LOGISTIC for Model Selection
  Qinlei Huang, St. Jude Children’s Research Hospital, Memphis, TN; Liang Zhu, St. Jude Children’s Research Hospital, Memphis, TN
Keywords: macro
Pages: 12 Size: 406 Kb 
tweet!  A SAS® Macro to address PK timing variables issues
  Timothy J Harrington, Dataceutics inc, Pottstown, PA
Keywords: macro
Pages: 14 Size: 71 Kb 
tweet!  A Mental Health and Risk Behavior Analysis of American Youth Using PROC FACTOR and SURVEYLOGISTIC
  Deanna Schreiber-Gregory, North Dakota State University
Keywords: Proc Surveylogistic Proc Factor behavioral health risky behaviors NDSU SAS healthcare
Pages: 23 Size: 630 Kb 
tweet!  A SAS® Macro to Evaluate Balance after Propensity Score Matching
  Erin Hulbert, Optum Life Sciences, Eden Prairie, MN; Lee Brekke, Optum Life Sciences, Eden Prairie, MN
Keywords: macro
Pages: 12 Size: 127 Kb 
tweet!  Methodology for Non-Randomized Clinical Trials: Propensity Score Analysis
  Dan Conroy, Ph.D., inVentiv Health, Burlington, MA
Keywords: Clinical Trials Non Randomized Propensity Scores
Pages: 5 Size: 123 Kb 
tweet!  Same Data, Separate MEANS – ‘SORT’ of Magic or Logic?
  Naina Pandurangi, inVentiv Health Clinical, Mumbai, India; Seeja Shetty, inVentiv Health Clinical, Mumbai, India
Pages: 8 Size: 76 Kb 
tweet!  Our Survival Confidence Intervals are not the Same!
  David Franklin, Quintiles Inc., Cambridge, MA
Keywords: Survival Confidence Intervals
Pages: 6 Size: 471 Kb 
tweet!  The path less trodden - PROC FREQ for ODDS RATIO
  Manjusha Gondil, Inventiv International Pharma Services Pvt. Ltd., Pune, India; Linga Reddy Baddam, Inventiv International Pharma Services Pvt. Ltd., Pune, India
Keywords: ODDS Ratio by PROC FREQ ODDS Ratio using SAS ODDS Ratio using PROC FREQ
Pages: 4 Size: 212 Kb 
tweet!  Creating and Customizing the Kaplan-Meier Survival Plot in PROC LIFETEST in the SAS/STAT® 13.1 Release
  Warren F. Kuhfeld, SAS Institute Inc., Cary, NC; Ying So, SAS Institute Inc., Cary, NC
Keywords: Kaplan-Meier Survival Plot
Pages: 35 Size: 2295 Kb 
Modeling Categorical Response Data
  Maura Stokes, SAS Institute, Cary, NC
tweet!  Automating Pharmaceutical Safety Surveillance process
  Pankaj Bhardwaj, Tata Consultancy Services Ltd, New Delhi, India; Chandramouli Raghuram, Tata Consultancy Services Ltd, Edison, NJ
Pages: 8 Size: 862 Kb 

Pharmaceutical SAS Users Group 2013   May 12-15, 2013 - Chicago, Illinois

Statistics and Pharmacokinetics
tweet!  Doctoring Your Clinical Trial with Adaptive Randomization: SAS® Macros to Perform Adaptive Randomization
  Jenna Colavincenzo, University of Pittsburgh, Pittsburgh, PA
Keywords: macro
Pages: 9 Size: 522 Kb 
tweet!  Probability Based Criteria in Early Phase Drug Development
  Howard Liang, inVentiv Health Clinical, Eden Prairie, MN
Keywords: Outliers Macro PROC MIXED Distant Data
Pages: 5 Size: 195 Kb 
Best Paper
tweet!  Combining Analysis Results from Multiply Imputed Categorical Data
  Bohdana Ratitch, Quintiles, Montreal, QC, Canada; Ilya Lipkovich, Quintiles, NC; Michael O'Kelly, Quintiles, Dublin, Ireland
Keywords: multiple imputation categorical variables Rubin's combination rule normalizing transformations
Pages: 19 Size: 531 Kb 
tweet!  Adjusted proportion difference and confidence interval in stratified randomized trials
  Yeonhee Kim, Gilead Sciences, Seattle, WA; Seunghyun Won, University of Pittsburgh, Pittsburgh, PA
Pages: 8 Size: 432 Kb 
tweet!  ‘Case-Control’ the analysis of Biomarker data using SAS ® Genetic Procedure
  Jaya Baviskar, inVentiv Health Clinical, Mumbai, India
Pages: 8 Size: 240 Kb 
tweet!  Time to Event Analysis in the Pharmaceutical and Medical Device Industries
  Helen M. Chmiel, Experis Corporation, Kalamazoo, Michigan; Evan L. Ritzema, Experis Corporation, Kalamazoo, Michigan
Pages: 8 Size: 235 Kb 
tweet!  Oh Quartile, Where Art Thou?
  David Franklin, TheProgrammersCabin.com, Litchfield, NH
Keywords: Statistics Quartile
Pages: 5 Size: 169 Kb 
tweet!  SAS® 9.3: Better graphs, Easier lives for SAS programmers, PK scientists and pharmacometricians
  Alice Zong, Janssen Research & Development, LLC, Spring House, PA
Keywords: SAS ODS Graphics PK PK/PD modeling Pharmacokinetics Pharmacodynamics Data Visualization
Pages: 8 Size: 430 Kb 
Introduction to Bayesian Analysis Using SAS® Software
  Maura Stokes, SAS Institute Inc., Cary, NC

Pharmaceutical SAS Users Group 2012   May 13-16, 2012 - San Francisco, California

Statistics & Pharmacokinetics
tweet!  Leverage SAS/Genetics Package to perform Biomarker Drug Response Analysis on Pharmacogenomic Data
  Deepali Gupta, GCE Solutions, Mansfield, MA; Shirish Nalavade, Independent Consultant, Mansfield, MA
Pages: 8 Size: 115 Kb 
Best Paper
tweet!  Computing Initial Values for Pharmacokinetic ML Nonlinear Regression via genetic algorithms and parallel genetic algorithms
  Francisco Juretig, Nielsen, Buenos Aires, Argentina
Keywords: genetic algorithms nonlinear regression pharmacokinetics statistics likelihood emax parallel
Pages: 11 Size: 545 Kb 
  Marina Komaroff, Noven Pharmaceuticals Inc., New York, NY
Pages: 7 Size: 472 Kb 
tweet!  Arriving ‘Normally' at t-test for a treatment combination
  Naina Pandurangi, PharmaNet/i3, Mumbai, India
Pages: 7 Size: 140 Kb 
tweet!  Pattern-Mixture Models as Linear Combinations of Least Squares Means from MMRM with Delta Method Variance Estimation
  Bohdana Ratitch, Quintiles, Montreal, Quebec, Canada; Michael O'Kelly, Quintiles, Dublin, Ireland
Keywords: pattern-mixture models MMRM least squares means
Pages: 15 Size: 271 Kb 
  Vanessa Rubano, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT; Modesta Wiersema, Boehringer Ingelheim Pharma GmbH & Co. KG., Biberach, DE
Pages: 8 Size: 166 Kb 
tweet!  Automated forward selection for Generalized Linear Models with Categorical and Numerical Variables using PROC GENMOD
  Manuel Sandoval, Pharmanet-i3, Mexico City, Mexico
Keywords: Statistics automatization GLM Generalized Linear Models Forward selection Stepwise selection SAS PROC GENMOD
Pages: 5 Size: 33 Kb 
tweet!  A SAS® Macro for Biomarker Analysis using Maximally Selected Chi-Square Statistic With Application in Oncology
  Quan Jenny Zhou, Eli Lilly and Company, Indianapolis, IN; Bala Dhungana, Eli Lilly and Company, Indianapolis, IN
Keywords: SAS macro biomarker Maximally Chi-Square Oncology
Pages: 8 Size: 372 Kb 
Communicating Clinical Trial Safety Results the Statistical Graphic Way
  Mat Soukup, U.S. Food and Drug Administration

Pharmaceutical SAS Users Group 2011   May 8-11, 2011 - Nashville, Tennessee

Statistics and Pharmacokinetics
tweet!  Incorporating Graphics into Summary Report Tables using ODS and GTL
  Qinghua (Kathy) Chen, Genentech Inc., South San Francisco, CA
Keywords: SAS Graphs Graphics Summary Report ODS GTL Forest Plot Blobbogram
Pages: 10 Size: 208 Kb 
tweet!  Formulas Calculating Risk Estimates and Testing for Effect Modification and Confounding
  Manojkumar B Agravat, Tampa, Florida
Pages: 44 Size: 832 Kb 
Best Paper
tweet!  Implementation of Pattern-Mixture Models Using Standard SAS/STAT Procedures
  Bohdana Ratitch, Quintiles, Montreal, Quebec, Canada; Michael O'Kelly, Quintiles, Dublin, Ireland
Keywords: pattern-mixture models multiple imputation monotone missing pattern
Pages: 10 Size: 105 Kb 
tweet!  A Modular Approach of Reporting Meta Analysis Statistics Using Forest Plots
  Vikash Jain, eClinical Solutions, A Division of Eliassen Group, New London, CT
Keywords: Meta Analysis Forest Plot GTL Template
Pages: 8 Size: 166 Kb 
tweet!  Caution: Hazards Crossing! Using the Renyi Test Statistic in Survival Analysis
  Matthew Davis, M.S., University of Pennsylvania, Philadelphia, PA; Sharon X. Xie, Ph.D., University of Pennsylvania, Philadelphia, PA
Pages: 9 Size: 191 Kb 
tweet!  Statistical Analysis of Adverse Events in Randomized Clinical Trials Using SAS
  Dongsun Cao, ICON Clinical Research, Durham, NC; Xiaomin He, ICON Clinical Research, North Wales, PA
Keywords: Treatment-emergent adverse events, Chi-square test, Fisher's exact test, Cochran-Armitage trend test, Exposure-adjusted incident rate, Nonparametric approach, General linear mixed model, Cross-over ...
Pages: 12 Size: 457 Kb 
tweet!  Estimating Sample Size through Simulations
  Wuchen Zhao, University of Southern California, Los Angeles, CA; Arthur X. Li, City of Hope National Cancer Center, Duarte, CA
Pages: 6 Size: 112 Kb 
tweet!  Implementation of Pairwise Fitting Technique for Analyzing Multivariate Longitudinal Data in SAS
  Madan Gopal Kundu, Indiana University Purdue University at Indianapolis, Indianapolis, IN
Keywords: Joint modeling Mixed model Multivariate longitudinal data Pairwise fitting approach Correlation between evolutions Marginal correlation
Pages: 12 Size: 207 Kb 
tweet!  Using SAS® for Modeling and Simulation in Drug Development – A Review and Assessment of Some Available Tools
  Melvin Munsaka, TGRD, Deerfield, Illinois; Michael Carniello, TGRD, Deerfield, Illinois
Keywords: modeling simulation
Pages: 10 Size: 274 Kb 
tweet!  Evaluating Safety Signals in Clinical Trials: the Dirichlet-NBD Model Implementation with SAS
  Yuqin Li, inVentiv Clinical Solutions, Indianapolis, IN; Xiaohai Wan, Eli Lilly and Company, Indianapolis, IN
Keywords: dirichlet DMD adverse events NBD negative binomial
Pages: 7 Size: 94 Kb 

Pharmaceutical SAS Users Group 2010   May 23-26, 2010 - Orlando, Florida

Statistics & Pharmacokinetics
tweet!  Using SAS® to Compute Partial Correlation
  Jianxin Lin, Merck & Inc.;Aiming Yang, Merck & Inc.;Arvind Shah, Merck & Inc.
Keywords: Partial Correlation PROC CORR PROC REG and PROC GLM
Pages: 5 Size: 85 Kb 
tweet!  Two-piecewise Random Coefficient Model Using Proc Mixed
  Shengjie Wu, St. Jude Children's Research Hospital
Keywords: Random Coefficient Model Proc Mixed
Pages: 6 Size: 277 Kb 
tweet!  Using SAS Proc Power to Perform Model-based Power Analyses for Clinical Pharmacology Studies
  Peng Sun, Merck & Co., Inc.
Keywords: Proc Power Power Analyses Clinical Pharmacology Studies
Pages: 11 Size: 91 Kb 
tweet!  Linear Mixed Models in Clinical Trials using PROC MIXED
  Danyang Bing, ICON Clinical Research;Xiaomin He, ICON Clinical Research
Pages: 12 Size: 462 Kb 
Best Paper
tweet!  Assessing superiority/futility in a clinical trial: from multiplicity to simplicity with SAS®
  Phil d'Almada, DCRI;Laura Aberle, DCRI
Keywords: superiority/futility clinical trial:
Pages: 9 Size: 47 Kb 
tweet!  Dynamic Determination of Mixed Model Covariance Structures in Double-blind Clinical Trials
  Matthew Davis, Omnicare Clinical Research
Keywords: Mixed Model Covariance Structures Double-blind Clinical Trials
Pages: 7 Size: 203 Kb 

Pharmaceutical SAS Users Group 2009   May 31 - June 3, 2009 - Portland, Oregon

Statistics & Pharmacokinetics
tweet!  Modeling the Treatment Effect on a Median of a Percent Change from Baseline in a Log-normal Variable Using SAS Procedure NLMIXED
  Aiming Yang
Pages: 5 Size: 99 Kb 
tweet!  The Existence of Maximum Likelihood Estimates for the Logistic Regression Model
  William McCarthy
Pages: 12 Size: 109 Kb 
tweet!  Illustrative Logistic Regression Examples using PROC LOGISTIC: New Features in SAS/STAT® 9.2
  Robert Downer
Keywords: ROC logistic regression model selection graphics
Pages: 11 Size: 472 Kb 
tweet!  Using PROC IML to Generate Weighted ChiSquare Statistics
  Daniel DiPrimeo
Keywords: PROC IML Weighted Chi-Square PROC Freq stratified binomial trials confidence intervals point estimates
Pages: 8 Size: 68 Kb 
tweet!  Distribution curves graphic, with patterned areas between minimum and maximum ranges using SAS®.
  Sylvain Cadieux
Keywords: SAS graph program gplot procedure graphic shaded area minimum maximum range annotate data
Pages: 7 Size: 1017 Kb 
tweet!  Detection of multiple outliers in univariate datasets
  Marek Solak
Pages: 7 Size: 207 Kb 
tweet!  Adhoc analysis of Site by Treatment Interaction
  Alan Davis
Pages: 9 Size: 47 Kb 
tweet!  A Little Stats Won't Hurt You
  Nathaniel Derby
Keywords: Descriptive statistics Statistical significance SAS
Pages: 18 Size: 194 Kb 
Best Paper
tweet!  ROC analysis for the evaluation of continuous biomarkers: Existing tools and new features in SAS® 9.2
  Sanghyuk Shin
Keywords: biomarkers ROC sensitivity specificity diagnostic Logistic procedure
Pages: 15 Size: 260 Kb 
tweet!  Confidence Intervals for the Binomial Proportion with Zero Frequency
  Xiaomin He
Keywords: Binomial Proportion Confidence Intervals Zero Frequency Wilson (Score) Confidence Interval SAS Macro.
Pages: 6 Size: 60 Kb 
tweet!  Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS® PROC NLMIXED
  Jing Su
Keywords: Pharmacokinetic (PK) Compartmental Models Multiple dose Superposition SAS PROC NLMIXED
Pages: 9 Size: 161 Kb 
tweet!  Concepts and Ideas for Developing and Maintaining a Utility Toolbox of SAS Statistical Procedures
  David Carr
Pages: 6 Size: 40 Kb 
tweet!  Don't Be Loopy: Re-Sampling and Simulation the SAS® Way
  David Cassell
Pages: 18 Size: 240 Kb 

Pharmaceutical SAS Users Group 2008   June 1-4, 2008 - Atlanta, Georgia

Statistics & Pharmacokinetics
tweet!  Sample Size Estimation for Trials of Recurrent Events
  Kuolung Hu, Amgen
Keywords: Poisson regression model recurrent event data Anderson-Gill Model sample size estimation.
Pages: 8 Size: 171 Kb 
tweet!  Sample size estimation for (Bio)equivalence Testing between two treatments
  Madan Kundu, i3 Statprobe
Keywords: sample size proc power bioequivalence crossover design replicated crossover sas macro
Pages: 13 Size: 375 Kb 
tweet!  Sample Size Estimation Through Simulation of a Random Coefficient Model by Using SAS
  Junliang Chen, Talecris Biotherapeutics, Inc
Keywords: Sample size Random coefficient model Lung densitometry Longitudinal studies
Pages: 8 Size: 103 Kb 
tweet!  Statistical Approach to Establishing Bioequivalence
  William McCarthy, MMRI
Pages: 12 Size: 131 Kb 
Best Paper
tweet!  Approximate Simultaneous Nonparametric Confidence Intervals for All-Pairwise Comparisons and Comparisons with a Designated (Control) Group in a One-Way Layout Using the SAS System
  Paul Juneau, MMS Holdings, Inc.; Aditya Sikka, MMS Holdings, Inc.; Jiawei Qiao, MMS Holdings, Inc.; Michelle Gayari, MMS Holdings, Inc.
Keywords: nonparametric statistical methods multiple comparison procedures one-way layout SAS macro
Pages: 19 Size: 295 Kb 
tweet!  Use SAS Programming to Calculate AUC in Pharmacokinetic Studies
  John He, Barr Laboratories
Keywords: SAS PK AUC Methods Comparison
Pages: 8 Size: 314 Kb 
  Suhas Sanjee, MaxisIT Inc
Keywords: Logistic Regression PROC GENMOD Adverse Event Logistic Regression Safety Analysis Dynamic Model Generation macro
Pages: 8 Size: 55 Kb 
tweet!  Using ESTIMATE and CONTRAST Statements for Customized Hypothesis Tests
  Hanyu Chen, CAZ Consulting Corporation
Pages: 8 Size: 135 Kb 
Best Paper
tweet!  A SAS Macro for Single Imputation
  Shuping Zhang, Merck & Co., Inc.; Jane Liao, Merck & Co., Inc.; Xingshu Zhu, Merck & Co., Inc.
Keywords: Missing data Mean Multiple Imputation data imputation methods RANNOR macro
Pages: 8 Size: 64 Kb 
tweet!  Bayesian Data Analysis Using %WinBUGS
  Lei Zhang, Celgene
Keywords: WinBUGS SAS %WinBUGS MCMC Bayesain Data Analysis WinBUGS Analysis File Markov chain Monte Carlo
Pages: 18 Size: 394 Kb    Download the codedownload (.zip, 28 Kb)

Pharmaceutical SAS Users Group 2007   June 3-6, 2007 - Denver, Colorado

Statistics & Pharmacokinetics
tweet!  The ROC Curve Method for the Assessment of Diagnostic Accuracy
  William F McCarthy, Maryland Medical Research Institute; Nan Guo, Maryland Medical Research Institute
Keywords: ROC curve diagnostic accuracy single diagnostic test macro
Pages: 12 Size: 163 Kb 
tweet!  Exploratory Visualization of Correlation Matrices
  Shi-Tao Yeh, GlaxoSmithKline
Keywords: correlation matrix scatter plot ellipses Loess matrix iteration process interactive graphs DS2CONST
Pages: 17 Size: 3538 Kb 
tweet!  Effects of Multicollinearity in All Possible Mixed Model Selection
  George C Fernandez, University of Nevada - Reno
Pages: 18 Size: 1852 Kb 
tweet!  A SAS Macro to Calculate the Ankle Brachial Index
  Rita A Dale, Colorado Prevention Center
Keywords: ankle-brachial index peripheral arterial disease macro
Pages: 4 Size: 70 Kb 
tweet!  Cochran-Armitage Trend Test Using SAS
  Hui Liu, Merck & Co., Inc
Keywords: Cochran-Armitage trend test dose-response binary response SAS
Pages: 11 Size: 81 Kb 
tweet!  Comparison of a Non-Parametric Rank-Sum Test Based on a SAS® Calculation of the Exact Null Distribution to Dunn's and Miller's Procedures
  April E Slee, Axio Research; Alice Birnbaum, Axio Research; Paul Stutzman, Axio Research
Keywords: nonparametric preclinical Dunn look-up Miller rank test
Pages: 12 Size: 95 Kb 
tweet!  SAS® Markov chain Monte Carlo (MCMC) Simulation in Practice
  Scott Patterson, GSK; Shi-Tao Yeh, GSK
Keywords: Bayes Monte Carlo Markov Chain distribution
Pages: 20 Size: 2170 Kb 
Best Paper
tweet!  Hypothesis Testing: An SQL Analogy
  Paul D Sherman, self; Leroy Bracken, self
Keywords: missing data Null hypothesis outer join consolidated pivot table SQL
Pages: 5 Size: 173 Kb    Download the presentationdownload (.zip, 632 Kb)
tweet!  Challenge the Specs
  Catherine M Edwards, PPD
Keywords: shell programming programmer CRF protocol SAP specifications specs AE table listing figure clinical trial
Pages: 7 Size: 60 Kb 
tweet!  Implementing Worst Rank Imputation using SAS
  Eric Qi , Merck; Qian Wang , Merck Sharp & Dohme (Europe), Inc.
Keywords: worst-rank imputation missing data
Pages: 10 Size: 114 Kb 
tweet!  SAS Macros to Detect and Evaluate Statistical Outliers
  Marek K Solak , Schering-Plough Research Institute, Monisha Dey , Schering-Plough Research Institute
Keywords: Macros Hofer-Rickard Grubbs Ferguson
Pages: 8 Size: 72 Kb 

Pharmaceutical SAS Users Group 2006   May 21-24, 2006 - Bonita Springs, Florida

Statistics & Pharmacokinetics
tweet!  Heuristic Algo: Backward Elimination Process for a Model
  Varsha C. Shah, University of North Carolina
Keywords: backward elimination procedure
Pages: 7 Size: 103 Kb 
tweet!  Generating Half-normal Plot for Zero-inflated Binomial Regression
  Zhao Yang, University of South Carolina; Xuezheng Sun, University of South Carolina
Keywords: half-normal plot zero-inflated binomi proc nlmixed simulation
Pages: 12 Size: 643 Kb 
tweet!  Macros to Create Quality Control (QC) Documents
  Xiaoyu Liu, ClinForce, Inc.; Hong Xiao, Eli Lilly & Company
Keywords: Quality Control QC documents Validation Macro Extract
Pages: 13 Size: 459 Kb 
Best Paper
tweet!  Sample Size Calculation and Timeline Estimate for Progression-Free Survival
  Chung-Kuei Chang, Cephalon, Inc.
Keywords: sample size calculation progression-free interval-censored power
Pages: 10 Size: 59 Kb 
tweet!  Analyzing Ordinal Repeated Measures Data Using SAS®
  Bin Yang, Eli Lilly and Company
Keywords: ordinal response GEE random-intercepts Proc Nlmixed Proc Genmod Proc IML categorical ordinal
Pages: 8 Size: 86 Kb 
tweet!  From GLM to GLIMMIX-Which Model to Choose?
  Patricia B. Cerrito, University of Louisville, Louisville, KY
Pages: 7 Size: 110 Kb 

Pharmaceutical SAS Users Group 2005   May 22-25, 2005 - Phoenix, Arizona

Statistics & Pharmacokinetics
tweet!  A SAS Macro for Analyzing Quality of Life data: NCIC-CTG standard Method
  Don (Dongguang) Li, NCIC-CTG
Keywords: Health Related Quality of Life (HRQOL) Statistical analysis SAS macros
Pages: 5 Size: 35 Kb 
tweet!  Smoothing pharmacokinetic and pharmacodynamic profiles
  Naum M. Khutoryansky, Novo Nordisk, Inc.
Keywords: Smoothing Pharmacokinetic Profiles Nonlinear Regression
Pages: 5 Size: 159 Kb 
tweet!  Using Procedure-Based ODS Data Components in Statistical Reporting
  Vincent J. Faber, DM-STAT,Inc.
Keywords: ODS Output Delivery Results Components Propensity
Pages: 10 Size: 74 Kb 
tweet!  Calculating posterior probability of the maximum contrast using proc iml
  Akira Wakana, Banyu Pharmaceutical Co., Ltd.; Isao Yoshimura, Tokyo University of Science; Chikuma Hamada, Tokyo University of Science
Keywords: phase II clinical trial dose-response contrast
Pages: 6 Size: 73 Kb 
tweet!  Power Analysis and Sample Size Estimation using Bootstrap
  Xiaomei Peng, Eli Lilly and Company
Keywords: Simulatioin Statistical power Sample size Bootstrap
Pages: 7 Size: 30 Kb 
tweet!  %KMPlot - An Enhancement of SAS PROC Lifetest
  Weifeng Xu, merck
Keywords: SAS PROC LIFETEST Kaplan-Meier Survival Analysis SAS Macro
Pages: 8 Size: 163 Kb 
tweet!  Noncompartmental pharmacokinetics and bioequivalence analysis
  Arturo Soto-Matos, PharmaMar; Bernardo de Miguel-Lillo, PharmaMar
Keywords: pharmacokinetics noncompartmental bioequivalence
Pages: 10 Size: 275 Kb 
Best Paper
tweet!  Analyzing and Displaying Study Data in Clinical Trials Made Easy
  Denise J. Smith, Mayo Clinic - Cancer Center Statistics
Keywords: QOL macros graphs tables
Pages: 15 Size: 210 Kb 

Pharmaceutical SAS Users Group 2004   May 23-26, 2004 - San Diego, California

Statistics and Pharmacokinetics
tweet!  Graph the R Matrix in Linear Mixed Model
  Jian Wu, Roche Products Australia; Peter Button, Roche Products Australia
Keywords: Mixed Model Covariance Structure R Matrix Longitudinal Data
Pages: 8 Size: 225 Kb 
tweet!  SAS Application in 2 * 2 Crossover Clinical Trial
  Wuwei (Wayne) Feng, Eli Lilly & Company; Dong Ding, MedFocus, Inc.
Keywords: 2 * 2 Crossover Clinical Trial SAS
Pages: 10 Size: 336 Kb 
tweet!  Automate Pharmacodynamic Analyses of Repeated Measure in Clinical Trials Using SAS Mixed Procedure
  Adeline Yeo, Eli Lilly and Company; Grace Li, Eli Lilly and Company
Keywords: pharmacodynamic analyses proc MIXED cross-over design parallel design covariace structures
Pages: 5 Size: 307 Kb 
Best Paper
tweet!  Simultaneous Nonparametric Inference in a One-Way Layout Using the SAS System
  Paul Juneau, Pfizer Global Research & Development
Keywords: multiple comparison procedures nonparametric inference drug discovery one-way layout unequal sample sizes
Pages: 17 Size: 92 Kb 
tweet!  The Analysis of Gene Markers and the Use of SAS Procedures to Examine MicroArray Data
  Patricia B. Cerrito, University of Louisville
Pages: 14 Size: 471 Kb 
tweet!  Using PROC LOESS with Sparse Data
  Kenneth S. Liu, Merck; Alison Kellock, Merck
Keywords: Macro Akaike Information Criterion
Pages: 7 Size: 66 Kb 
tweet!  2D-Gel Proteomics in Biomarker Discovery
  Mark Carpenter, Auburn University; Craig Rowell, University of Alabama at Birmingham; Coral Lamartiniere, University of Alabama at Birmingham
Keywords: proteomics genomics MIXED GLM MULTTEST Biomarkers Fisher's Exact Test
Pages: 7 Size: 496 Kb 
tweet!  Statistical Simulations for Sample Size Calculation with PROC IML
  Izabella Peszek, Merck & Co., Inc
Keywords: sample size IML simulation power
Pages: 8 Size: 136 Kb 
tweet!  Box Plots for Pharmaceutical Studies: One of the Better Ways to Get a Clear Picture of Study Results
  Mary P. Cowmeadow, BioStat Reports
Keywords: Box Plots Radar plots nonparametric blocking variables spaghetti plots
Pages: 8 Size: 550 Kb 
tweet!  Traditional Repeated Measures Analysis Versus Random Coefficients Models Using PROC MIXED
  Radhi Abdulnabi, Pfizer
Keywords: Longitudinal data Repeated measures Random coefficients Mixed Model
Pages: 9 Size: 34 Kb 
tweet!  Incremental Methods of Imputation for Longitudinal Data with Informative Missingness
  Naum M. Khutoryansky, Novo Nordisk Pharmaceuticals.
Pages: 4 Size: 135 Kb 

Pharmaceutical SAS Users Group 2003   May 4-7, 2003 - Miami, Florida

Statistics & Pharmacokinetics - Reporting & Analysis
tweet!  Implementing Constrained or Balanced-Across-the-Centers Randomization with SAS v8 Procedure PLAN
  Cindy Song, Merck & Co; Olga Kuznetsova, Merck & Co.
Keywords: Procedure Plan Allocation Schedule Permuted Blocks Randomization Constrained Randomization Restricted Randomization Clinical Trials
Pages: 8 Size: 87 Kb 
tweet!  A SAS Macro to Automate The Covariance Structure Determination in Repeated Measures Data Analysis
  Don Li, National Cancer Institute of Canada - CTG
Keywords: Covariance structure Repeated measures Data Mixed model SAS Macro
Pages: 4 Size: 81 Kb 
tweet!  Using SAS® to Perform a Single-Stage Multiple Comparison Procedure for All Pair-wise Comparisons in a One-Way Layout with Unequal Variances
  Paul Juneau, Pfizer Global Research and Development
Keywords: heteroscedasticity one-way layout PROBMC function single-stage multiple comparison procedure
Pages: 6 Size: 154 Kb 
tweet!  Benchmarking Forecasting Practices in Pharmaceuticals
  Chaman Jain, St. John's University, Department of Eonomics
Keywords: Forecasting Models Forecasting software/system Forecasting Process Salary of forecasting professionals
Pages: 6 Size: 81 Kb 
tweet!  Using SAS to Evaluate the Integrals for Sample Size and Power Analysis Calculations
  Xingshu Zhu, Merck & Co; Shuping Zhang, Merck & Co.
Keywords: Integrals sample size power area
Pages: 6 Size: 208 Kb 
tweet!  SAS Macro to Create ADDL Records to Estimate Dosing Not Represented in the Collected Data, In a NONMEM Population Pharmacokinetic Analysis Dataset
  Richard Schneck, Eli Lilly and Company; Mike Heathman, Eli Lilly and Company; Lynn Reynolds, Eli Lilly and Company
Keywords: ADDL Macro NONMEM Estimated Pharmacokinetic Dosing
Pages: 6 Size: 126 Kb 
tweet!  Likelihood Approach in Estimation and Testing Problems Involving Overlapping Grouped Data
  Daniel Bonzo, InfoVision Consultants, Inc.
Keywords: count sets cut points interval data MLEs right-censored observations Newton-Raphson Method
Pages: 8 Size: 169 Kb 
tweet!  Using SAS software for Multilevel Models in Survival Analysis
  Gisela Silva, University of Sao Paul; Antonio Lima, University of Sao Paulo
Keywords: Survival analysis multilevel models proportional hazards semiparametric Cox model mixed models
Pages: 4 Size: 151 Kb 
tweet!  Confidence Intervals in Analysis and Reporting of Clinical Trials
  Guangbin Peng, Eli Lilly and Company
Keywords: confidence interval significance testing distribution-free clinical trial
Pages: 8 Size: 149 Kb 
tweet!  Single Dose Bioassay - A SAS Approach
  John Sparkes, Biostat Consulting; May Tang, Aventis Pasteur Limited.
Keywords: single-dose bioassay statistical potency clinical pre-clinical
Pages: 4 Size: 50 Kb 
tweet!  Using Model Fitting Information and PROC PLOT to Select the Type of Variance-Covariance Structure
  Radhi Abdulnabi, Pfizer
Keywords: covariance structure repeated measures Akaike's Information Criterion Schwarz's Bayesian Criterion general linear mixed model
Pages: 8 Size: 287 Kb 
tweet!  Selecting Balanced Cohorts for Comparison in Observational Research
  Craig Roberts, NDCHealth; John Gerlach, TekSystems
Keywords: propensity score sampling logistic regression observational study retrospective database analysis parallel arrays transpose
Pages: 4 Size: 116 Kb 
Best Paper
tweet!  Statistical Processing and Analysis of Proteomic and Genomic Data
  Mark Carpenter, University of Alabama at Birmingham; Sijian Zhang, University of Alabama at Birmingham; William E. Grizzle, University of Alabama at Birmingham
Keywords: data smoothing multivariate statistics clustering wavelets discrimination
Pages: 4 Size: 324 Kb 
Best Paper
tweet!  Parameter Estimation for Incomplete Bivariate Longitudinal Data in Clinical Trials
  Naum Khutoryansky, Novo Nordisk Pharmaceuticals, Inc.
Keywords: bivariate data longitudinal data incomplete data clinical trials
Pages: 6 Size: 51 Kb 
tweet!  Using SAS Software for a Numerical Approximation and the Area Under a Curve Calculation
  Shi-Tao Yeh, GlaxoSmithKline; Ellen Forman, GlaxoSmithKline
Keywords: Trapezoidal Simpson's Rule AUC PROC NLIN
Pages: 6 Size: 117 Kb 

Pharmaceutical SAS Users Group 2002   May 5-8, 2002 - Salt Lake City, Utah

Statistics & Pharmacokinetics - Reporting & Analysis
tweet!  Simulating Attrition and Visual Models of Type I and Type II Errors
  Haftan Eckholdt, Albert Einstein College of Medicine
Keywords: attrition bootstrapping simulation longitudinal analysis
Pages: 10 Size: 1220 Kb 
tweet!  Dynamic Letter Assignment in Efficacy Tables in Clinical Trial Research
  Zaizai Lu, Kendle international Inc.; Medea Meng, Kendle International, Inc; David Shen, CTG Consulting
Keywords: efficacy statistics order letter pairwise p values
Pages: 6 Size: 78 Kb 
tweet!  Some Analysis Methods for Behavioral Toxicology Data
  Richard Allen, Peak Statistical Services
Keywords: drill-down graphics HTML repeated measures logistic regression GEE GENMOD MIXED GLIMMIX LOESS
Pages: 8 Size: 153 Kb 
tweet!  The 800 Pound Gorilla: Taking on the Challenge of Globally Standardizing AE and Medication Reporting
  Deborah Harper, Pfizer Global Research and Development; Jennifer Tjernagel, Pfizer Global Research and Development
Keywords: standards requirements specification adverse events medications reporting coding dictionary ITT TESS
Pages: 4 Size: 128 Kb 
Best Paper
tweet!  Fast Two-Sample Permutation Tests, Even When One Sample is Large, that Efficiently Maximize Power Under Crude Monte Carlo Sampling
  J.D. Opdyke, Economic Consulting Group - Andersen, LLP
Keywords: permutation test resampling Monte Carlo collector's problem PROC PLAN PROC MULTTEST PROC TWOSAMPL maximizing power telecommunications parity test
Pages: 10 Size: 193 Kb 
tweet!  Bayesian Analysis of Population Bioequivalence Using the Independence Chain Algorithm in PROC MIXED
  Richard McNally, Colorado State University
Keywords: population bioequivalence Monte Carlo Markov chain independence chain proc mixed
Pages: 6 Size: 155 Kb 
tweet!  Two Step Approach to Automatically Generate ESTIMATE Statements for Pair-wise Treatment Comparisons
  Eric Qi, Merck & C; Guanghan Liu, Merck & Co
Keywords: PROC MIXED ESTIMATE LSMEANS pair-wise comparison OM
Pages: 4 Size: 95 Kb 

Pharmaceutical SAS Users Group 2001   May 20-23, 2001 - Boston, Massachusetts

Statistics & Pharmacokinetics
tweet!  A Data Null Reporting Method
  Frank Senk, FMDE Solutions Inc, Lansdale, PA
Pages: 6 Size: 106 Kb 
tweet!  An Application of Continual Reassessment Method Using SAS System
  Naoki Ishizuka, National Cancer Center Research Institute, Tokyo, Japan
Pages: 4 Size: 378 Kb 
tweet!  Automatic Estimation of Dixon's Test for Extreme Values Using a SAS® Macro Driven Program
  Don Li, Biovail Contract Research, Toronto, ON, Canada; Edmond Edwards, Biovail Contract Research, Toronto, ON, Canada
Keywords: Outlier Dixon SAS macro
Pages: 4 Size: 80 Kb 
Best Paper
tweet!  Can standards be implemented effectively without compromising science?
  Amy Morris, Merck Research Laboratories, Blue Bell, PA
Pages: 4 Size: 65 Kb 
tweet!  Fitting Generalized Additive Models with the GAM Procedure
  Dong Xiang, SAS Institute Inc., Cary, NC
Keywords: Generalized Additive Model Nonparametric Regression
Pages: 8 Size: 179 Kb 
tweet!  Fitting Gompertz Nonlinear Mixed Mode l to Infancy Growth Data with SAS® version 8 Procedure NLMIXED
  Cindy Q. Song, Merck & Co., Inc, Rahway, NJ; Olga M. Kuznetsova, Merck & Co., Inc, Rahway, NJ
Keywords: Proc NLMIXED Gompertz growth model
Pages: 8 Size: 204 Kb 
tweet!  Imputation Techniques Using SAS Software For Incomplete Data In Diabetes Clinical Trials
  Naum M. Khutoryansky, Novo Nordisk Pharmaceuticals, Inc., Princeton, NJ; Won-Chin Huang, Novo Nordisk Pharmaceuticals, Inc., Princeton, NJ
Keywords: missing data imputation diabetes clinical trials
Pages: 4 Size: 46 Kb 
tweet!  Nonlinear Least Squares Analysis of HIV Viral Load Data - Aids in Parameter Estimation
  Peter Gaccione, Harvard Medical School
Pages: 8 Size: 172 Kb 
tweet!  Power and Sample Size Determination for Linear Models
  JohnM.Castelloe, SASInstitute Inc., Cary,NC; Ralph G. O'Brien, Cleveland Clinic Foundation, Cleveland, OH
Keywords: power analysis anova regression mixed models statistics
Pages: 14 Size: 577 Kb 
tweet!  Testing the Trend of a Response Curve to an Increasing Sequence of Doses: A SAS Macro to Automate the Analysis
  Donghui Zhang, Merck Research Laboratories, Rahway, NJ
Keywords: macro
Pages: 4 Size: 145 Kb 
tweet!  Using SAS® ? Version 8.1 Output Delivery System to Automate Two Sample Test Selection and Summarization
  Becki Bucher Bartelson, netRegulus, Denver, CO
Keywords: Output Delivery System Dynamic Test Selection ods
Pages: 4 Size: 35 Kb 

Pharmaceutical SAS Users Group 2000   May 7-10, 2000 - Seattle, Washington

Best Paper
tweet!  From Data to Study Report in One Step: A SAS® Macro for the 2,2,2 Crossover Design
  Amy Morris; Thomas E. Bradtreet
Keywords: macro
Pages: 5 Size: 358 Kb 
tweet!  A SAS® Tool for the Presentation and Statistical Analysis of Data from Bioavailability and Bioequivalence Studies
  Melvin S. Munsaka; Carl R. Haske
Pages: 8 Size: 125 Kb 
tweet!  Reducing Statisticians' Programming Load: Automated Statistical Analysis with SAS® and XML TM
  Michael C. Palmer; Cecilia Hale
Keywords: xml
Pages: 5 Size: 324 Kb 
tweet!  Exploratory Analysis for Efficient Data Mining
  Thomas H. Burger; Loren W. Burger, Jr.
Pages: 1 Size: 5 Kb 
tweet!  Using SAS® for the Statistical Analysis of Bivariate Primary Endpoint in a Clinical Trial of Chronic Fatigue Syndrome (CFS)
  Naum M. Khutoryansky; David R. Strayer; William A. Carter
Pages: 3 Size: 22 Kb 
tweet!  A Nonparametric Approach for the Statistical Analysis of Time to First Event in Censored Paired Data
  Roderick Lashley
Pages: 3 Size: 21 Kb 
tweet!  An Alternative to the Odds Ratio: A Method for Comparing Adjusted Treatment Group Effects on a Dichotomous Outcome
  P. Chris Holland
Pages: 5 Size: 35 Kb 
tweet!  Visualize Your Regression Analysis
  Fan Xu
Pages: 7 Size: 734 Kb 
tweet!  Meta-Analysis with Linear and Nonlinear Multilevel Models
  Eugene Komaroff; Russell D. Wolfinger
Pages: 4 Size: 32 Kb 
tweet!  Random Simulation Methods for Computing Power and Sample Size for Tukey's Trend Test
  Benjamin Duncan
Pages: 6 Size: 39 Kb 
tweet!  Mixed Models Analysis Using JMP® Software 4.0
  George A. Milliken; Annie L. Dudley
Pages: 6 Size: 83 Kb 

Pharmaceutical SAS Users Group 1998   May 17-20, 1998 - San Francisco, California

tweet!  The Q System of Adverse Event Analysis and Reporting
  Mary Cowmeadow, Parke-Davis Pharmaceutical Research, Division of Warner Lambert, Company, Ann Arbor, Michigan
Pages: 8 Size: 30 Kb 
Use of Multivariate Techniques to Solve an Urgent, Real-Life Pharmaceutical Manufacturing Problem
  Karl Glaser, Syntex / Roche
tweet!  Using SAS Arrays to Estimate Regression Coefficients
  Tesfaye Liranso, Hoechst Marion Roussel, Kansas City, Missouri
Keywords: array
Pages: 5 Size: 13 Kb 
tweet!  A FRAMES Application to Estimate Sample Size and Power for Clinical Trials
  Brian Mitchell, Above Average Consulting, Inc., Westerville, Ohio
Pages: 4 Size: 53 Kb 
tweet!  Some Aspects of Statistical Modeling to Develop a System for Pharmaceutical Industry Indicators Forecasting
  Alexander Visnevsky, Covance Periappoval Services Inc., Radnor, PA
Pages: 6 Size: 24 Kb 
tweet!  Pilot Trials as Screening Procedure in Generic Drug Product Development: Statistical Power and Influential Factors
  Yibin Wang, Ph.D., Biovail Corporation International, Mississauga, Canada,\; Shelley Bull, Ph.D., Samuel Lunenfeld Research Institute, Toronto, Canada
Pages: 5 Size: 38 Kb 

Pharmaceutical SAS Users Group 1997   May 11-14, 1997 - Hilton Head, South Carolina

tweet!  Controlling For Experimentwise Type II Error: Optimum Patient Allocation For A Three Armed, Parallel, Randomized, Controlled Clinical Trial With Binary Outcomes
  Benjamin Duncan, Glaxo Wellcome Inc., Research Triangle Park, North Carolina
Pages: 13 Size: 563 Kb 
tweet!  Visual Component Analysis: Interactive Graphical Modeling in SAS and ViSta/XLispStat
  Richard A. Faldowski, Ph.D., Medical University of South Carolina, SC.
Pages: 13 Size: 827 Kb 
tweet!  Statistical Programming Workflow Process Improvement at Fujisawa USA
  Jay Erdman, Fujisawa USA; Paul Gilbert, DataCeutics Inc.
Pages: 4 Size: 240 Kb 
tweet!  The Jonckheere-Terpstra Nonparametric Ordered Alternatives Test
  Nestor Rohowsky, Statistics and SAS Programming Consultant
Pages: 10 Size: 247 Kb 
tweet!  Obtaining Group Sequential Test Boundaries With SAS
  William J. Stager, Hoechst Marion Roussel, Bridgewater, N.J.; Jessie J. Yun, Hoechst Marion Roussel, Bridgewater, N.J.
Pages: 4 Size: 250 Kb 
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